stimuli responsive polymer integrated targeted nanomedicine is designed for combined cancer-targeted therapy and multimodal imaging using a facile preparation method. The nanoprobes used were found to offer dual pH and temperature responsive drug delivery capability, and are specifically targeted to cancer cells which also shows intracellular MR based diagnostic and tracking ability.
25 Feb 2021 Stimuli-responsive drug-delivery systems have emerged as potential tools for advanced treatment of cancers. Versatile nano-carriers
Pris: 1619 kr. Inbunden, 2018. Skickas inom 5-8 vardagar. Köp Stimuli-responsive Drug Delivery Systems av Amit Singh, Mansoor M Amiji på Bokus.com. Drug Deliv, 2015; 22(2): 145–155! 2014 Informa Healthcare USA, Inc. DOI: 10.3109/10717544.2014.887157 CRITICAL REVIEW Classification of stimuli–responsive polymers as anticancer drug delivery systems Bita Taghizadeh1, Shahrouz Taranejoo2, Seyed Ali Monemian3, Zoha Salehi Moghaddam4, Karim Daliri5, Hossein Derakhshankhah6, and Zaynab The stimuli-responsive nanocarriers for drug delivery to tumors towards precision imaging, effective therapy and theranostics. The nanocarriers could accumulate and penetrate tumors, and target cancer cells for achieving different applications and functions by responding to the external and internal stimuli.
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• Hydrogels may undergo phase transition or structural change in response to stimuli. • Stimuli are exogenous (light) or endogenous triggers in the tumor microenvironment. 2019-01-01 · Physical stimuli-responsive vesicles in drug delivery: Beyond liposomes and polymersomes 1. Introduction. The aim of drug delivery is to increase therapeutic efficacy. Drug delivery vesicles can aid in this 2.
When drugs or biomolecules are transported to certain regions of the brain, these changes can induce cargo release from the drug carrier to treat abnormal cells or tissues. Among them, strategies utilizing stimuli‐responsive delivery systems are highly desirable to regulate glycemia with minimal patient effort and improve the quality of life for diabetic patients.
Stimuli Responsive Drug Delivery Systems: From Introduction to Application: 9780863802225: Medicine & Health Science Books @ Amazon.com.
The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. Stimuli-responsive systems have become a promising way to deliver and release payloads in a site-selective manner.
Title: Stimuli-Responsive Molecularly Imprinted Polymers for Drug Delivery: A Review VOLUME: 5 ISSUE: 2 Author(s):Francesco Puoci, Francesca Iemma and Nevio Picci Affiliation:Dipartimento di Scienze Farmaceutiche, Universita della Calabria - Edificio Polifunzionale, Arcavacata di Rende (CS) 87036, Italy. Keywords:Molecularly imprinted polymers, stimuli-responsive systems, intelligent drug delivery
inbunden, 2018. Skickas inom 5-7 vardagar. Köp boken Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications (ISBN Pris: 622 kr. häftad, 2015. Skickas inom 5-7 vardagar. Köp boken Development of Novel Stimuli-Responsive Drug Delivery Systems av Safaei Nikouei Nazila Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications – Köp som bok, ljudbok och e-bok.
Multistimuli-responsive drug delivery systems are sensitive to more than one stimulus. In the realm of cancer drug delivery, numerous stimuli-responsive carrier systems, in the form of conjugates, dendrimers, liposomes, and micelles, have been developed (Heidarli et al. 2017).
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In vitro studies of the SDDS made it possible to visualize faster cellular uptake at pH 6.8 than at pH 7.4 because of the re-exposure of cationic charges and subsequent successful delivery of CPT to the cell nucleus. c) Thermoresponsive drug delivery system: The use of temperature as a signal has been justified by the fact that the body temperature often deviates from the physiological temperature (37°C) in the presence of pathogens or pyrogens. This deviation is a useful stimulus that activates the release of therapeutic agents from various temperature-responsive drug delivery systems for diseases Therefore, various stimuli-responsive PMs have been developed for “smartly” controlling drug release as well as drug efficacy. 12,13 The idea of stimuli-responsive drug delivery systems comes from the fact that the tumor tissue possesses a variety of unique features compared with the normal tissue, including acidic pH, altered redox potential, and overexpressed proteins and enzymes.
12, 13 In this review, we will focus on the different stimuli‐responsive systems for diabetic therapeutic delivery, including pH‐responsive, glucose‐responsive, and external physical trigger
stimuli-responsive drug release. ABSTRACT Nanotechnology has become an outgrowing field in novel drug delivery system. It confers several merits over conventional formulations like increased solubility and bioavailability, targeted drug delivery and a decreased dose of the drug.
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Stimuli-responsive materials, which exhibit changes in one or more properties in response to an external trigger, have gained interest due to their tunability and versatility. Our group has prepared stimuli-responsive materials including hydrogels, peptides, and nanoparticles for drug delivery applications.
The traditional design of stimuli-responsive NMs is based on the incorporation of drug molecules into the nanocarrier, which is prepared from pH-sensitive building blocks. However, under acidic conditions, drug delivery systems tend to demonstrate burst drug release instead of extended-release.
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Biological stimuli responsive drug carriers based on keratin for triggerable drug delivery
The stimuli-responsive release may result in significantly enhanced therapeutic efficacy and minimized possible side effects.